Buffy the Vampire Slayer star Nicholas Brendon dies aged 54

His family confirmed that the star passed away in his sleep from ‘natural causes”. (Picture: Shutterstock; Getty)

Nicholas Brendon, who played Xander on Buffy the Vampire Slayer, has died aged 54.

His family confirmed that the star passed away in his sleep from ‘natural causes’.

Brendon had previously suffered a heart attack in 2023 and had been diagnosed with a congenital heart defect.

He also had cauda equina syndrome, which causes severe back pain and other symptoms. In 2021, he underwent surgery to treat the syndrome.

His family paid tribute to him in a statement released to The Hollywood Reporter.

“We are heartbroken to share the passing of our brother and son, Nicholas Brendon. He passed in his sleep of natural causes,’ it read.

PHILADELPHIA, PA - JUNE 02: Actor Nicholas Brendon attends Wizard World Comic Con Philadelphia 2017 - Day 2 at Pennsylvania Convention Center on June 2, 2017 in Philadelphia, Pennsylvania. (Photo by Gilbert Carrasquillo/Getty Images)
Nicholas’s family have paid tribute to their late brother and son.(Picture: Gilbert Carrasquillo/Getty Images)

‘Most people know Nicky for his work as an actor, and for the characters he brought to life over the years. In recent years, Nicky has found his passion in painting and art. Nicky loved to share his enthusiastic talent with his family, friends and fans. He was passionate, sensitive, and endlessly driven to create.

The statement contined by saying those who knew Brendon understood that art was the ‘purest reflection of who he was’ and acknowledging his struggles in the past.

FILE MARCH 20, 2026: Nicholas Brendon, best known as Xander in the "Buffy, The Vampire Slayer" series, has died at age 54. 370100 07: Nicholas Brendon as Xander Harris stars in 20th Century Fox's "Buffy The Vampire Slayer Year 5." (Photo by Online USA)
Nicholas played Xander on Buffy the Vampire Slayer (Picture: Online USA)

‘Our family asks for privacy during this time as we grieve his loss and celebrate the life of a man who lived with intensity, imagination, and heart,’ it finished. ‘Thank you to everyone who has shown love and support.’

Since the news of Brendon’s death broke, several of his Buffy co-stars have paid tribute to the actor.

‘My Sweet Nicky, thank you for years of laughter, love and Dodgers,’ wrote Alyson Hannigan, who played Willow Rosenberg. ‘I will think of you every time I see a rocking chair. I love you. RIP’

Emma Caulfield, meanwhile, shared a video of Brendon discussing their duet from the Season 6 musical episode on Instagram.

Editorial use only Mandatory Credit: Photo by 20thC.Fox/Everett/Shutterstock (402833h) 'Buffy the Vampire Slayer' - Nicholas Brendon Alyson Hannigan, Sarah Michelle Gellar, Charisma Carpenter 'Buffy the Vampire Slayer' TV Series
Brendon’s Buffy costars have shared tributes following his death. (Picture: 20thC.Fox/Everett/Shutterstock)

‘My heart is heavy,”’she captioned the post. ‘I can’t put into words just how this has hit me. Let this clip of us giving it our all be a placeholder. Rest Nicky. Rest. I love you.’

While Brendon was best known for playing Xander, he also had roles on Private Practice, Without a Trace, and Faking It.

Arguably, though, his best-known role outside of Buffy was on Criminal Minds, where he played Kevin Lynch across seasons three to ten.

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